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Excision Biotherapeutics

All articles tagged with #excision biotherapeutics

health2 years ago•2 min saved

"Promising Results: CRISPR Cure for HIV Shows Success in Initial Patient Trials"

Excision BioTherapeutics has shared data from the first human clinical trial of their CRISPR cure for HIV, called EBT-101. The treatment instructs a CRISPR system to target and eliminate the HIV hiding in a person's cells. The trial involved three patients who had undetectable levels of HIV due to antiretroviral therapy (ART). No serious adverse effects were observed, and the therapy was detectable in the blood of all three participants four weeks after treatment. However, the announcement did not provide data on whether the therapy successfully prevented HIV rebound after stopping ART. Excision plans to present more trial data in 2024 and administer a larger dose of EBT-101 to six more participants in the next phase of the study.

via Big Think|

#clinical-trial #crispr #excision-biotherapeutics

health2 years ago•5 min saved

"CRISPR Therapy Shows Promise in HIV Cure Trials"

The search for a cure for HIV continues, with CRISPR gene editing technology showing promise. Chinese scientists have used CRISPR to edit the CCR5 gene in an HIV patient, but further research is needed to achieve complete eradication of the virus. Excision BioTherapeutics has started a clinical trial for its CRISPR-based drug, EBT-101, which targets three sites within the HIV genome. Challenges in finding a cure include the rapid mutation and resistance of the virus, as well as safety concerns and the need for long-term studies. While a CRISPR-based therapy may take time to become widely available, it offers a promising solution for developing a curative treatment for HIV.

via Labiotech.eu|

#antiretroviral-therapy #crispr #excision-biotherapeutics

health2 years ago•3 min saved

"Promising Results: CRISPR Gene Editing Shows Potential as HIV Cure"

Excision BioTherapeutics has shared data from the first human clinical trial of a CRISPR cure for HIV, called EBT-101. The treatment instructs a CRISPR system to target and eliminate the HIV hiding in a person's cells. The trial involved three participants who had undetectable levels of HIV prior to starting the study. None of the patients experienced serious adverse effects from the CRISPR therapy, and the four mild adverse effects observed resolved on their own. The primary purpose of the trial was to test the safety and tolerability of the therapy, with plans to have eligible participants stop taking antiretroviral therapy (ART) to see if their HIV rebounded. More trial data is expected to be presented in 2024.

via Freethink|

#clinical-trial #crispr #excision-biotherapeutics

health2 years ago•5 min saved

CRISPR Gene Editing: A Potential Cure for HIV and PFAS Destruction

Three patients have received CRISPR gene-editing therapies in an effort to eradicate HIV from their bodies. The potential treatment, called EBT-101, is safe and has caused no major side effects. Six more men will be treated with higher doses, and data will be presented at a medical conference next year. The therapy aims to permanently remove viral DNA without cutting human DNA. While there have been promising results in animals, success in humans is still uncertain. A cure for HIV is needed to end the pandemic, and Excision BioTherapeutics' therapy could potentially be a lifelong cure.

via The Mercury News|

#crispr-gene-editing #ebt-101 #excision-biotherapeutics