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Epithelial Mesenchymal Transition Emt

All articles tagged with #epithelial mesenchymal transition emt

Revolutionary Treatment Overcomes Metastasis and Chemotherapy Resistance in Cancer
health2 years ago

Revolutionary Treatment Overcomes Metastasis and Chemotherapy Resistance in Cancer

Scientists have made a groundbreaking discovery in cancer research by identifying a molecule called Netrin-1 that contributes to cancer metastasis and resistance to therapy. Blocking Netrin-1 reduces the process of epithelial-mesenchymal transition (EMT), which enables cancer cells to spread and acquire resistance to treatment. Early trials in humans have shown promise, with the administration of an anti-Netrin-1 antibody leading to a reduction in tumor formation, inhibition of EMT, and increased sensitivity to chemotherapy. Further research will explore the broader applicability of this treatment and its impact on survival rates in different types of cancers.

Targeting Netrin-1: A Promising Approach to Inhibit EMT and Tumor Growth in Endometrial Cancer
medical-research2 years ago

Targeting Netrin-1: A Promising Approach to Inhibit EMT and Tumor Growth in Endometrial Cancer

Researchers have discovered that pharmacological targeting of netrin-1, a protein involved in tumor progression and metastasis, can inhibit epithelial-mesenchymal transition (EMT) in cancer. EMT is a process that allows cancer cells to acquire invasive and migratory properties, contributing to tumor metastasis. Netrin-1 has been found to promote EMT and is associated with poor prognosis in various types of cancer. By interfering with netrin-1, it may be possible to inhibit EMT and potentially limit cancer progression and metastasis.