Tag

Drugdevelopment

All articles tagged with #drugdevelopment

health1 year ago•4 min saved

Revolutionary Weight Loss Drug Enhances Energy and Curbs Appetite Safely

Researchers at the University of Copenhagen have discovered that activating the Neurokinin 2 Receptor (NK2R) can safely reduce weight and reverse diabetes by increasing energy expenditure and reducing appetite without side effects. This breakthrough could lead to more effective treatments for obesity and type 2 diabetes, benefiting millions worldwide. The study, published in Nature, shows promising results in both mice and non-human primates, and the University holds patent rights for this potential new therapy.

via SciTechDaily|

#diabetes #drugdevelopment #health

health-and-medicine2 years ago•3 min saved

"Breakthrough Antibiotic Offers Hope Against Drug-Resistant Superbugs"

Researchers at Harvard University and Roche have developed an experimental antibiotic named zosurabalpin that effectively kills the drug-resistant superbug Acinetobacter baumannii. This breakthrough represents a new class of drugs, as it targets Gram-negative bacteria, which are notoriously difficult to treat due to their complex membrane structures and resistance strategies. Zosurabalpin, which is already in clinical trials, works by clogging a transport system in the bacteria, leading to lethal toxicity. This discovery is significant as it offers hope against infections with mortality rates of 40 to 60 percent and could lead to more treatments for drug-resistant infections.

via Ars Technica|

##acinetobacterbaumannii #antibioticresistance

health-and-medicine2 years ago•4 min saved

"Promising New Antibiotic Class Emerges in Battle Against Drug-Resistant Superbugs"

Scientists have discovered a new class of antibiotic named Zosurabalpin, which has proven effective against the drug-resistant superbug CRAB (Carbapenem-resistant Acinetobacter baumannii) in lab tests and mouse models. CRAB is a critical pathogen with a high mortality rate, and the new antibiotic works by disrupting the bacteria's protective membrane. While promising, Zosurabalpin's effectiveness in humans has yet to be confirmed through clinical trials. This breakthrough could potentially address the growing global health threat of antimicrobial resistance, which causes over 1 million deaths annually.

via Daily Mail|

##antibioticresistance #crab

health-and-medicine2 years ago•4 min saved

"Breakthrough Antibiotic Emerges to Combat Superbugs with Unprecedented Resistance-Fighting Method"

Researchers have developed a new antibiotic called Zosurabalpin, which shows promise in treating drug-resistant Acinetobacter baumannii, a deadly bacteria responsible for serious infections and high mortality rates. This novel antibiotic, which is now in phase 1 clinical trials, operates by disrupting the bacteria's outer membrane, a method that could potentially be applied to other resistant Gram-negative bacteria. The breakthrough comes after a 50-year gap since the last class of antibiotics was approved to combat such pathogens, offering hope in the global fight against antimicrobial resistance.

via CNN|

##acinetobacterbaumannii #antibioticresistance