Tag

Deprescribing

All articles tagged with #deprescribing

health2 years ago

"Dementia risks: Deprescribing, hormone therapy, and acid reflux drugs under scrutiny"

A study led by researchers at the Beth Israel Deaconess Medical Center reveals that efforts to deprescribe medications for dementia patients are failing, as there is an increase in overall medication use following a dementia diagnosis. Despite the importance of simplifying medication regimens and reducing adverse drug events, deprescribing guidelines and efforts are not effectively implemented. The study highlights a potential gap in clinical practice and raises concerns about the increased use of central nervous system-active medications, which can adversely affect cognitive function. The findings suggest missed opportunities to reduce burdensome polypharmacy and deprescribe medications with high safety risks or limited likelihood of benefit.

health2 years ago

Exploring the Safety of Stopping MS Treatment in Elderly Patients

A new study led by the P-HOPER Center at the University of Houston College of Pharmacy aims to determine whether older adults with multiple sclerosis (MS) can safely stop taking disease-modifying therapies. The study, funded by a $1.6 million grant, will analyze deprescribing outcomes in elderly MS patients and evaluate the safety and effectiveness of discontinuing disease-modifying agents (DMAs) in this population. The researchers will compare outcomes for patients who continue on DMAs versus those who are deprescribed these medications, with the goal of optimizing prescribing practices and improving health outcomes and quality of life for older MS patients.

health2 years ago

"Essential Medications to Discuss with Your Health Care Team"

It is important to regularly evaluate the need for medications, as some may no longer be necessary or carry risks of side effects. Common medications like antihistamines, heartburn medications, antibiotics before dental procedures, aspirin, statins after age 74, sleep aids, hormone replacement therapy, and testosterone supplementation may not be needed indefinitely and should be discussed with healthcare professionals. Each individual's situation is unique, and regular evaluation of medication benefits and risks is crucial for maintaining optimal health.

healthcare2 years ago

Rapid Detection of Mild Cognitive Impairment in Primary Care

Primary care is an ideal setting for screening and detecting mild cognitive impairment (MCI) using brief cognitive assessment tools. Alberto Freire, MD, presented a stepwise algorithm for diagnosing and treating MCI, emphasizing the importance of functional assessment and deprescribing medications that contribute to cognitive disorders. Freire recommended picture-based tests and caregiver-oriented tests for cognitive assessment, as well as the use of the Mongil test for assessing activities of daily living. He also highlighted the need for comprehensive laboratory testing and neuroimaging. Nondrug therapies, such as cognitive training and rehabilitation, were emphasized, as there is currently no drug that is an improvement over nondrug therapies for MCI.

health2 years ago

"Deprescribing": Reconsidering Medication Use in Older Adults.

Many older adults may be on too many medications and could benefit from a medication review with their primary care doctor. About 57% of people age 65 years or older take five or more medications regularly – a concept known as polypharmacy. Patients and caregivers can ask for an honest conversation with their doctor. By reevaluating their medications, older adults can actually lower their chances of potentially harmful side effects, and avoid the spiral of being prescribed even more medications.

health2 years ago

Navigating the Challenges of Antidepressant Withdrawal

Antidepressants are a critical intervention for millions of people experiencing depression, but once the drugs have done their job, how well do we manage what comes next? A 2019 major review of studies found that about half of those coming off the drugs will experience withdrawal symptoms, with half of those describing them as severe. The UK health regulator, Nice, amended its guidance on how to support people coming off antidepressants, acknowledging the severity and length of withdrawal symptoms can vary. In Australia, support is available at Beyond Blue on 1300 22 4636, Lifeline on 13 11 14, and at MensLine on 1300 789 978.