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Chandelier Cells

All articles tagged with #chandelier cells

neuroscience2 years ago

"Unpredictable Reactions: Neurons' Surprising Responses"

New research from the Netherlands Institute for Neuroscience reveals that chandelier cells, a unique type of brain cell, become active during unexpected events, playing a crucial role in signaling and adaptation in response to surprising stimuli. The study used a novel mouse model to observe and understand the behavior of chandelier cells, showing their sensitivity to unexpectedness, habituation, and structural changes in synaptic connections. This comprehensive study sheds light on the role of these inhibitory neurons in the cortex, crucial for processes such as learning from unexpected circumstances.

neuroscience2 years ago

"Unveiling the Adaptive Neural Mechanism for Robust and Flexible Learning: A Groundbreaking Study"

A study conducted by researchers at Johns Hopkins University School of Medicine and the Max Planck Florida Institute for Neuroscience has revealed an adaptive inhibitory pattern of interconnections in the brain that supports the robust and flexible acquisition of new behaviors. The study focused on chandelier cells (ChCs), a subgroup of interneurons, and found that they selectively inhibit individual pyramidal neurons, contributing to the refinement and re-organization of cortical circuits during learning. These findings highlight the significance of interneuron diversity and provide valuable insights into the neural mechanisms underlying adaptive learning.