Brain's Lymphatic Blockages Linked to Migraines, Study Finds
Originally Published 1 year ago — by ScienceAlert
Researchers from the University of North Carolina School of Medicine have found that calcitonin gene-related peptides (CGRP) may block cerebrospinal fluid drainage in the brain, contributing to migraine pain. Their study on mice showed that CGRP prevents fluid flow in the brain's lymphatic system, causing pressure and pain. This discovery helps explain the effectiveness of CGRP-targeting migraine treatments and suggests potential sex differences in migraine prevalence due to lymphatic dysfunction.
