"Unlocking the Power of T-Cell Therapy: Master Regulator Holds Key to Cancer Breakthrough"
Researchers at the UC Davis Comprehensive Cancer Center have discovered a "kill switch" on the CD95 receptor that can trigger the death of cancer cells. The protein on the receptor, known as Fas, can program cancer cells to self-destruct. This breakthrough could potentially lead to the development of new cancer drugs that boost the activity of CD95 receptors, providing a new weapon against tumors. While immune-based therapies have shown promise, they have had limited effectiveness against many cancer types. The newly discovered "kill switch" could not only terminate tumor cells but also enhance the effectiveness of immunotherapies, offering a potential one-two punch against cancer. However, no CD95-boosting drugs have entered clinical trials yet.
