A prominent gene editing researcher from UC Berkeley, Fyodor Urnov, and venture capitalist Johnny Hu are launching a startup to scale personalized CRISPR medicines, aiming to treat ultra-rare genetic mutations and overcome regulatory and commercial challenges.
Biotech startup eGenesis successfully transplanted a gene-edited pig kidney into a living human, marking a significant milestone in organ transplantation. The company aims to expand its gene-editing technology to include liver and heart transplants in the next two years, potentially disrupting the $15 billion market for organ transplants. While the success of the pig kidney transplant offers hope for addressing the shortage of human donor organs, further research and data are needed to determine the long-term viability and safety of such transplants. The company also envisions creating organs in pigs that do not require immunosuppression, potentially revolutionizing the field of organ transplantation.
Shares of biotech startup Structure Therapeutics surged over 30% after its experimental obesity pill showed promising results in an early-stage trial, helping participants lose an average of 10 pounds in four weeks. The company plans to conduct further midstage trials for diabetes and obesity treatment. Structure's pill belongs to the same class as Novo Nordisk's Ozempic and Wegovy, which have gained popularity for their weight loss benefits. Analysts predict the obesity drug market could reach $100 billion globally by the end of the decade, and Structure's pill could compete with other oral obesity drugs from Eli Lilly, Novo Nordisk, and Pfizer. The availability of cheaper and more convenient pill versions of GLP-1s could increase patient access and expand the market.
Academy Award-winning actress Halle Berry has taken a job as chief of communications at Pendulum Therapeutics, a San Francisco-based biotech startup focused on probiotic supplements. Berry, who was diagnosed with Type 1 diabetes at a young age, became a fan of the company's products and has been taking them for a year. She will be promoting Pendulum's Glucose Control, which contains five strains of probiotics that are meant to help manage sugar levels in those with Type 2 diabetes.