All articles tagged with #antibiotic tolerance
The study identifies KL1, a host-targeted compound that reduces reactive oxygen and nitrogen species in macrophages, thereby resensitizing intracellular bacterial persisters like S. aureus to antibiotics and improving treatment outcomes in various infection models.
Antibiotic tolerance is a covert threat that researchers have only recently begun to explore. Tolerant bacteria often exist in a dormant state, neither growing nor dying but putting up with the antibiotic until they can "reawaken" once the stress is gone. Researchers are calling for more research into antibiotic tolerance with the hope that it will lead to more robust treatments in both infectious diseases and cancers. Vibrio cholerae is rapidly evolving resistance against various types of antibiotics, and doctors are concerned.
Antibiotic tolerance is a covert threat that researchers have only recently begun to explore. Tolerance happens when a bacterium manages to survive for a long time after being exposed to an antibiotic. While antibiotic-resistant bacteria flourish even in the presence of an antibiotic, tolerant bacteria often exist in a dormant state, neither growing nor dying but putting up with the antibiotic until they can “reawaken” once the stress is gone. Tolerance has been linked to the spread of antibiotic resistance.