The Science Behind Premature Gray Hair Unveiled.
TL;DR Summary
Scientists have discovered that melanocyte stem cells (McSCs) get trapped in the follicle bulge as people age, which stops them from developing into melanocytes and producing hair color. The researchers found that McSCs can switch between a stem cell state and a transit-amplifying state, but they become stuck in the follicle bulges. This unique behavior of McSCs may be responsible for graying and loss of hair color. The researchers suggest that modulating McSC mobility may represent a new approach for the prevention of hair graying.
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