Mixed Results: MIND Diet Trial and Chronic Constipation's Impact on Brain Health

A randomized trial conducted by the Rush Alzheimer's Disease Center found no significant improvement in cognitive function or changes in brain morphology after three years among older adults following the MIND diet compared to a control diet group with mild caloric restriction. The MIND diet, which combines elements of the Mediterranean and DASH diets, has been previously associated with preserving brain health. The study suggests that previous mixed results in diet trials may be due to research bias, confounding factors, or differences in study design and execution.