Revolutionizing Mitochondrial DNA Editing with a Cutting-Edge Tool.

Researchers have developed a new method of editing mitochondrial DNA using MutH, a bacterial nickase, and TALEs. The approach is much more precise and efficient than previous methods and has no off-target effects on mitochondrial DNA. While the technology is still in an early developmental stage, it may one day be used to treat mitochondrial genetic disorders and age-related disorders caused by accumulated mitochondrial damage.