Revolutionary DNA Editing Technique Enhances Efficiency, Precision, and Reliability

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Source: Phys.org
Revolutionary DNA Editing Technique Enhances Efficiency, Precision, and Reliability
Photo: Phys.org
TL;DR Summary

Researchers at the Max Planck Institute for Evolutionary Anthropology have developed a new method for DNA editing that significantly improves efficiency, precision, and reliability. By inhibiting competing repair pathways, the team achieved point mutations in up to 93% of chromosomes in cell populations, while minimizing unwanted insertions, deletions, and rearrangements. The method was successfully tested on 58 different target sites in human cells and corrected pathogenic mutations in cells derived from patients with genetic diseases. While the implications for curing human diseases are promising, further research and development are needed before applying the method to patients.

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