Mapping the Mouse Brain: Unveiling the Secrets of Human DNA and Cell Types

Scientists have created a comprehensive and high-resolution transcriptomic and spatial atlas of cell types in the entire adult mouse brain. Using single-cell RNA sequencing and spatial transcriptomics analysis, they identified 34 classes, 338 subclasses, 1,201 supertypes, and 5,322 clusters or types of cells in the mouse brain. The atlas provides detailed information about the molecular and anatomical properties of different cell types, allowing researchers to study the relationships between cell types and their spatial distribution in the brain. The data is available through the Allen Brain Cell Atlas, an online platform that enables researchers to explore and analyze the cell types in the mouse brain.
- A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain Nature.com
- Scientists unveil complete cell map of a whole mammalian brain National Institutes of Health (.gov)
- New Cell Atlases Reveal Untold Variety in the Brain and Beyond Quanta Magazine
- Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain Nature.com
- Decoding Humanity: How Mapping the Mouse Brain Unveils Human Secrets SciTechDaily
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