Mapping the Intricate Landscape of the Mammalian Brain

Scientists have created a complete cell atlas of a whole mammalian brain, specifically the mouse brain, providing detailed information on the type, location, and molecular characteristics of over 32 million cells. This atlas serves as a map for understanding the human brain and lays the foundation for the development of precision therapeutics for mental and neurological disorders. The atlas includes information on cell structure, transcriptome, and epigenome, as well as neurotransmitters and neuropeptides used by different cells. The findings were funded by the NIH's BRAIN Initiative and published in Nature. The next step is to complete cell maps of the human brain and nonhuman primate brain.