Advancements in RNA Editing Revolutionize Viral Engineering and Patient Treatment

Researchers have developed a new RNA editing tool that utilizes a type III Crispr system to modify RNA viruses. This breakthrough could revolutionize the development of RNA therapies, accelerate the engineering of human viruses, and facilitate drug testing. The system allows for precise editing of RNA viruses, enabling scientists to study the effects of genetic modifications on virulence and drug resistance. Additionally, it holds potential for treating single-base DNA disorders and restoring mutant proteins. While further improvements are needed for wider adoption, this RNA editing approach marks the beginning of a new era in genome engineering at the RNA level.
- 'This is just the beginning': RNA editing set to democratise viral engineering Chemistry World
- Newly engineered CRISPR enzyme for editing DNA could improve patient treatment Phys.org
- CRISPR-based gene editing gets smaller, better "scissors" Interesting Engineering
- Using a cutting enzyme and an RNA repair enzyme to modify RNA virus genomes Phys.org
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