The Impact of Sugars on Brain Plasticity, Learning, and Memory

Complex sugar molecules called glycosaminoglycans (GAGs) with sulfate groups have been found to affect brain plasticity in mice, potentially influencing memory and learning. GAGs, particularly chondroitin sulfate, play a role in stabilizing synaptic connections in the brain. Altering the sulfation patterns of GAGs could have implications for repairing neural connectivity after injuries and understanding neurodegenerative diseases. Researchers are also investigating how GAGs and their sulfation patterns impact axon regeneration, which could lead to potential treatments for promoting recovery from neurodegenerative diseases or strokes.