Unveiling a Hidden Vulnerability in Prostate Cancer

An international research team has discovered a previously unknown weak spot in prostate cancer cells involving a component of the minor spliceosome, which is significantly increased in advanced prostate cancer and drives uncontrolled cell growth. Inhibiting this component led to a significant reduction in prostate cancer growth compared to standard therapies, offering potential for more effective, targeted treatments. This discovery may also have implications for other types of cancer. The research was supported by the US Prostate Cancer Foundation with a $1 million grant.