Uncovering the Secrets of Cell Division Reversal in Cancer Treatment

TL;DR Summary
Researchers at the Center for Molecular Medicine Norway have discovered the mechanisms behind the activation of Aurora B, an enzyme crucial for cell division. By disrupting the activity of Aurora B during cell division, the process becomes chaotic, leading to cell death. This knowledge can be used to develop new cancer treatments that block Aurora B activity and prevent cancer cells from dividing uncontrollably. The researchers used molecular dynamics simulation and hydrogen-deuterium exchange mass spectrometry to analyze the structure and dynamics of Aurora B.
- Cancer can be treated by blocking central conductor of cell division, study finds Phys.org
- A lack of commitment to proliferation Nature.com
- NIH study offers insights into how cells reverse their decision to divide National Institutes of Health (.gov)
- Study offers insights into how cells reverse their decision to divide Phys.org
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