Scientists Discover Enzyme 'Off Switch' to Combat Cholesterol and Inflammation

TL;DR Summary
Scientists at the University of Texas at Arlington discovered that blocking the enzyme IDO1 can restore macrophages' ability to process cholesterol during inflammation, potentially preventing diseases like heart disease, diabetes, and cancer. Targeting IDO1 and nitric oxide synthase could lead to new treatments for inflammation-related illnesses.
- Scientists Find an “Off Switch” for Cholesterol – And It Could Save Millions SciTechDaily
- Turning off the enzyme behind high cholesterol may pave path for new therapies for multiple inflammatory diseases Medical Xpress
- Scientists discover ‘off switch’ enzyme that could stop heart disease and diabetes ScienceDaily
- New enzyme can be "turned off" to restore cholesterol balance and reduce inflammation MSN
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