Adipose Tissue's Role in Cognitive Function Unveiled by Study

A study conducted by researchers at the University of Girona in Spain has found that adipose tissue (fat tissue) plays a role in co-regulating cognitive function. The study identified 188 genes associated with cognitive performance through RNA sequencing of adipose tissue in three patient cohorts. These genes were linked to synaptic function, anti-inflammatory signaling, vitamin metabolism, phosphatidylinositol metabolism, and the complement cascade. The researchers also found that targeted misexpression of candidate genes in fruit flies and mice significantly altered memory and learning. The study provides insights into the adipose-brain axis and potential diagnostic and therapeutic targets in adipose tissue.