"Unveiling the Bioelectrical Phase Transition that Initiates Vertebrate Heartbeats"

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Source: Nature.com
"Unveiling the Bioelectrical Phase Transition that Initiates Vertebrate Heartbeats"
Photo: Nature.com
TL;DR Summary

Researchers have discovered that a bioelectrical phase transition is responsible for patterning the first heartbeats in vertebrates. Using advanced imaging techniques and optogenetics, the study revealed that calcium signaling plays a crucial role in initiating the heartbeat, preceding cardiac differentiation. The findings provide new insights into the early development of the heart and could have implications for understanding heart defects and potential therapeutic interventions.

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