"Uncovering One Million New Components in the Human Genome"

Researchers at the University of Toronto's Donnelly Center for Cellular and Biomolecular Research have discovered nearly one million new exons in the human genome using a method called exon trapping. These exons, which are stretches of DNA expressed in mature RNA, were found to be mainly due to random mutation and are unlikely to play a significant role in human biology. The findings challenge assumptions about the accurate removal of non-protein-coding intron regions and could potentially impact our understanding of genetic diseases and the development of tools for predicting splice sites and aberrant splicing.