Sepsis-Protective Gene Turns Harmful in Older Mice
TL;DR Summary
A Nature study in mice shows that a gene that helps young organisms survive sepsis can increase mortality in older mice, suggesting ageing rewires how the body tolerates infection and could guide age-specific therapies.
- How ageing harms the body’s response to raging infection Nature
- Disease tolerance and infection pathogenesis age-related tradeoffs in mice Nature
- Should younger and older people receive different treatments for the same infection? Salk Institute for Biological Studies
- Age-Related Tradeoffs in Mouse Disease Tolerance BIOENGINEER.ORG
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