Mapping the Developing Human Heart to Understand Congenital Defects
TL;DR Summary
This study provides a detailed spatiotemporal map of gene expression and cellular dynamics during early human heart development, analyzing over 69,000 tissue spots and nearly 77,000 cells across 36 hearts, revealing diverse cell types, specialized conduction system components, and the formation of cardiac innervation and valves, thereby advancing understanding of human cardiogenesis.
Topics:health#cardiogenesis#cellular-dynamics#human-heart-development#science#spatial-transcriptomics#spatiotemporal-gene-expression
- Spatiotemporal gene expression and cellular dynamics of the developing human heart Nature
- Heart ‘blueprint’ offers insights into fetal development and congenital defects News-Medical
- Cross-sections of the developing heart (IMAGE) EurekAlert!
- Fetal Heart Map Illuminates Development and Origins of Congenital Defects Genetic Engineering and Biotechnology News
- Advancing the spatiotemporal atlas of the developing human heart Nature
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