KAIST Develops CRISPR-Based System for Precise RNA Modification in Living Cells
TL;DR Summary
KAIST researchers developed a precise RNA modification technology using CRISPR-Cas13 and a hyperactive NAT10 variant, enabling targeted acetylation of specific RNAs in living cells and animals, which could advance RNA-based therapies and gene regulation research.
- CRISPR-Cas13 allows selective modification of desired RNA in living cells Phys.org
- Targeted RNA acetylation via a dCas13-guided engineered acetyl-transferase Nature
- KAIST pioneers targeted RNA acetylation system for gene therapy advancements Chosun Biz
- New CRISPR tool enables precise chemical modification of RNA in living cells News-Medical
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