IL-10 Monocytes Explain Why Men Turn Off Pain Faster
TL;DR Summary
A Michigan State University study shows IL-10–producing monocytes actively resolve inflammatory pain; higher testosterone in males boosts these cells, leading to faster pain relief, while females’ monocytes are less active and pain persists longer. This immune-driven mechanism suggests non-opioid treatments that enhance IL-10 signaling could prevent chronic pain.
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- Why chronic pain lasts longer in women: Immune cells offer clues Medical Xpress
- New study probes why chronic pain lasts longer in women The Japan Times
- MSU study sheds light on why women experience longer-lasting pain WILX
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