Genetic Mapping Reveals Celtic Curse Hotspots Across Britain and Ireland

A new study using UK Biobank and Viking Genes data maps genetic risk for hereditary hemochromatosis (the so‑called Celtic curse) across Britain and Ireland, finding the highest carrier rates in north‑west Ireland, the Outer Hebrides, Northern Ireland, and parts of Scotland. The authors argue targeted genetic screening in these hotspots could uncover many undiagnosed cases and enable early, simple treatment (regular blood donation) to prevent liver damage, cancer, and arthritis, while regional diagnosis patterns reflect historical migration and may indicate underdiagnosis in several areas.