Chronic Stress and Neuronal Aging: Risks and Strategies for Healthy Brain Aging

TL;DR Summary
A study by UC San Diego researchers found that aging neurons exhibit molecular stress markers, such as stress granules and TDP-43 accumulation, which impair their ability to recover from stress and may contribute to neurodegenerative diseases like Alzheimer's and ALS. The research highlights potential targets for developing therapies to prevent these conditions.
- Molecular Stress in Old Neurons Increases Susceptibility to Neurodegenerative Diseases, Study Finds UC San Diego Today
- Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress Nature
- Stress significantly increases your dementia risk — here are 4 ways to fight back New York Post
- Chronic stress contributes to cognitive decline and dementia risk – 2 healthy-aging experts explain what you can do about it The Conversation
- Nash: Stress in the golden years The Mendocino Voice
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