Breakthrough in Appetite Control: New Neurons and GLP-1 Insights

TL;DR Summary
Researchers have discovered a new population of neurons in the hypothalamus that regulate appetite by expressing leptin receptors and the BNC2 gene. These neurons respond to hunger-suppressing signals and food-related cues. Disrupting these neurons in mice led to increased food intake and weight gain, highlighting their role in energy balance. This finding offers a potential new target for obesity treatments, providing hope for more effective therapies against the obesity epidemic.
- New Appetite Regulating Neurons Discovered Neuroscience News
- GLP-1 discovery may offer even better appetite suppression than Ozempic New York Post
- ‘Leptin’s last chance’: Mouse study says infamous weight loss drug failure could boost GLP-1s STAT
- Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety Nature.com
- Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain The Transmitter: Neuroscience News and Perspectives
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