Bicyclic Peptides Potently Inhibit SARS-CoV-2 in Super-Resolution Microscopy Study.

Super-resolution microscopy has revealed that the SARS-CoV-2 virus infects cells by binding a single virus to a single ACE2 receptor, contrary to previous theories. The low density of ACE2 receptors on cell membranes challenges the possibility of a virus particle binding to multiple receptors simultaneously. This new understanding could help in devising improved COVID-19 prevention and treatment methods.