Scientists Develop Bacteria Capable of Producing Unnatural Amino Acid and Tanzawaic Acid B at Large Scale

Engineers at the University of Delaware have successfully engineered bacteria to produce pN-Phe, a non-standard amino acid with potential medical applications. This breakthrough opens up possibilities for the development of unique vaccines and immunotherapies. The researchers used synthetic biology and genetic engineering techniques to create a system that autonomously produces nitrated proteins. The long-term goal is to optimize the process and expand it to other microorganisms, with the aim of refining the platform for applications in vaccines and immunotherapies.