Breakthrough: Scientists Achieve In Vivo Genetic Modification of Individual Cells

Scientists at ETH Zurich have successfully used CRISPR-Cas gene editing to simultaneously modify multiple genes in the cells of adult mice, creating a mosaic-like pattern. This technique allows for the study of genetic diseases caused by multiple genes in a single experiment, potentially reducing the need for animal experiments. The researchers applied this method to study the genetic disorder 22q11.2 deletion syndrome and discovered new insights into the disease. The approach has the potential to accelerate biomedical research and the development of targeted therapies for complex genetic diseases.