"Advancing mRNA Technology with Lipid Nanoparticles"

Michael J. Mitchell, an associate professor of bioengineering at the University of Pennsylvania, specializes in designing lipid nanoparticles (LNPs) to deliver mRNA inside human cells for potential applications in medicine, including cancer and other diseases. His lab uses microfluidics to create LNPs and has developed a new LNP that mimics a space shuttle to improve mRNA delivery efficiency. They have also successfully targeted the lungs of mice with LNPs and are working on crossing the blood-brain barrier for potential therapeutic applications.