"Uncovering Central Brain Systems in Psychosis: Insights from Neural Network Study"

Researchers have identified malfunctions in two critical brain systems—the "filter" and the "predictor"—in individuals with psychosis, shedding light on the underlying brain mechanisms. By studying young individuals with 22q11.2 deletion syndrome, the research offers insights into how these dysfunctions occur, potentially guiding future treatments and prevention strategies. The findings suggest that dysfunction of these brain systems makes it difficult to distinguish reality, leading to symptoms such as hallucinations and delusions. The study used advanced imaging and machine learning to confirm these dysfunctions, providing potential new targets for therapeutic interventions and offering implications for understanding and possibly preventing psychosis.