Oxytocin impacts amygdala response to anger in ASPD.

A recent study has found that oxytocin administration decreases amygdala activity in individuals with antisocial personality disorder (ASPD), bringing it closer to the levels observed in healthy individuals. The study involved 20 men and 18 women diagnosed with ASPD, and 20 male and 20 female healthy control participants. The administration of oxytocin seemed to modulate amygdala activation differently in individuals with ASPD and healthy controls. When individuals with ASPD were given oxytocin, the activity in their amygdala decreased.