Hippocampus Shrinkage: A Key Factor in Cognitive Decline

A study reveals that hippocampal shrinkage in the brain is associated with cognitive decline, independent of amyloid-beta plaques, a key marker of Alzheimer's disease. The research suggests that neurodegenerative diseases other than Alzheimer's contribute to cognitive decline, highlighting the complexity of dementia. The study involved 128 participants monitored over seven years, and the findings emphasize the need for broader diagnostic approaches in understanding cognitive impairment.