Anti-Aging Drug Duo Triggers Brain Myelin Loss in Mice, Study Finds

University of Connecticut researchers report that the anti-aging drug combination dasatinib and quercetin (D+Q) causes significant myelin loss and corpus callosum damage in mice, with younger animals affected more. The oligodendrocytes shift to a less mature, energy-stressed state, suggesting safety concerns for preventive use and offering new clues for understanding multiple sclerosis.