"Novel Antibiotic Eradicates Drug-Resistant Superbug"

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Source: Livescience.com
"Novel Antibiotic Eradicates Drug-Resistant Superbug"
Photo: Livescience.com
TL;DR Summary

A new synthetic compound, zosurabalpin, has been discovered as a promising antibiotic against the drug-resistant bacterial species CRAB (carbapenem-resistant Acinetobacter baumannii). This novel antibiotic targets CRAB using a unique attack strategy, disrupting the bacterium's outer membrane machinery. The compound is currently undergoing early-stage safety trials in humans and shows potential as a new class of antibiotic with a narrow target, reducing the impact on the body's microbiome. The discovery raises the possibility of LPS as a promising new target for future antibiotics against other gram-negative bacteria.

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