"Uncovering Five Variants of Alzheimer's Disease: A Potential Breakthrough in Treatment"

Scientists have identified five distinct biological variants of Alzheimer's disease, each with specific alterations in clusters of proteins related to inflammation, nerve cell growth, and other biological processes. This breakthrough discovery could lead to more personalized therapies or preventive measures for these subtypes, as well as hope for early diagnosis and intervention to delay the onset of symptoms of Alzheimer's disease. The research team used updated technology to analyze cerebrospinal fluid proteins and identified variations such as hyperplasticity, immune activation, RNA dysregulation, choroid plexus dysfunction, and blood-brain barrier impairment. This finding suggests that medications already tested may have falsely seemed to be ineffective or only slightly effective, and that some drugs may only work in specific Alzheimer's types.