"Gene Deletion Reverses Obesity-Related Mitochondrial Dysfunction"

A study from UC San Diego reveals that a high-fat diet causes mitochondria within fat cells to break apart, reducing their capacity to burn fat and leading to weight gain. Researchers identified a gene, RaIA, that controls this process and found that deleting it protected mice from excess weight gain. Understanding this mechanism brings us closer to developing targeted therapies for addressing weight gain and associated metabolic dysfunctions caused by obesity.