Unraveling the Genetic Links to Prostate Cancer Risk in Black Men

Scientists have discovered genetic mutations that may explain why Black men are at higher risk of developing prostate cancer, potentially leading to a test to identify those at greatest risk. The research identified mutations in DNA regulatory regions that control androgen receptor levels, which are frequently found in men with African ancestry but virtually absent in men of European ancestry. These findings could lead to a genetic test to predict which subset of men are most likely to develop the disease, potentially revolutionizing the management of prostate cancer and helping to close the survival gap between Black and white men.