mRNA Therapy Revitalizes Aging Immune System and Enhances Disease Response
TL;DR Summary
The study presents a novel approach to counteract immune decline in aging by using mRNA delivered to the liver to produce key immune factors (DLL1, FLT3-L, IL-7), which rejuvenates T cell production, enhances vaccine responses, and improves tumor immunotherapy efficacy in aged mice, without adverse effects or autoimmunity.
Topics:health#health-and-medicine#immune-aging#immunotherapy#liver-based-delivery#mrna-therapy#thymus
- Transient hepatic reconstitution of trophic factors enhances aged immunity Nature
- New study suggests a way to rejuvenate the immune system MIT News
- Scientists Discover Protein That Can Rejuvenate the Aging Immune System SciTechDaily
- mRNA rejuvenates aging immune system - the liver as a fountain of youth Deutsches Krebsforschungszentrum
- mRNA therapy restores T-cell production and boosts vaccine, cancer responses - CHOSUNBIZ Chosunbiz
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