"Early DAPT Within 72 Hours Shows Promise for Improved Stroke Outcomes"

A study published in the New England Journal of Medicine found that taking clopidogrel-aspirin within 72 hours of a mild ischemic stroke or high-risk TIA significantly reduces the risk of new strokes compared to aspirin alone, but doubles the risk of moderate to severe bleeding. The INSPIRES trial, which excluded patients with certain types of strokes or treatments, suggests that the benefits of dual antiplatelet therapy extend to a wider time window than previously considered, although caution is advised for patients with a history of bleeding.