"Breakthrough Looming: Crossing the Blood-Brain Barrier"

Scientists at the University of Pennsylvania have developed a new in vitro model of the blood-brain barrier, allowing them to test the delivery of lipid nanoparticles carrying proteins, antibodies, or mRNA therapies into the central nervous system. This breakthrough could lead to novel approaches for treating conditions like traumatic brain injury, stroke, and Alzheimer's, as well as pregnancy-related and retinal diseases. The study's findings, published in Nano Letters, show promise for overcoming the blood-brain barrier and advancing brain-targeted treatments.