Gilead's HIV Prevention Shot Achieves 100% Efficacy in Trials
TL;DR Summary
Gilead Sciences announced that its twice-yearly injectable HIV-1 capsid inhibitor, lenacapavir, demonstrated 100% efficacy in preventing HIV infections in cisgender women during the Phase 3 PURPOSE 1 trial. The independent Data Monitoring Committee recommended stopping the blinded phase of the trial and offering open-label lenacapavir to all participants. This marks the first Phase 3 HIV prevention trial to show zero infections, highlighting lenacapavir's potential as a significant new tool for HIV prevention.
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