FDA Concludes: No Evidence of Weight-Loss Drugs Causing Suicidal Thoughts

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Source: FDA.gov
FDA Concludes: No Evidence of Weight-Loss Drugs Causing Suicidal Thoughts
Photo: FDA.gov
TL;DR Summary

The FDA has conducted a preliminary evaluation of reports of suicidal thoughts or actions in patients taking glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for type 2 diabetes and obesity, finding no evidence of a causal link. While additional evaluations are ongoing, including a meta-analysis of clinical trials and an analysis of postmarketing data, patients are advised not to stop taking GLP-1 RAs without consulting a healthcare professional. Healthcare professionals should monitor and advise patients to report any new or worsening depression, suicidal thoughts, or unusual changes in mood or behavior. The FDA encourages reporting of side effects involving GLP-1 RAs or other medicines to the FDA MedWatch program.

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