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Vulnerable Plaques

All articles tagged with #vulnerable plaques

health-medicine1 year ago•5 min saved

"Early PCI Shows Promise in Reducing Risks of Vulnerable Coronary Plaques"

The PREVENT trial of preventive coronary stents targeting vulnerable plaques showed promising results at the American College of Cardiology meeting, with an 89% reduction in major cardiac events at 2 years. However, concerns about the small number of events, overestimation of outcome rates, open-label design, and limited clinical translation suggest caution in interpreting the results. While the study provides hope in understanding vulnerable plaques, it's too early to change current PCI practice, and further studies are needed to validate these findings.

via Medscape|

#cardiology #health-medicine #percutaneous-coronary-intervention

health1 year ago•4 min saved

"Early Preventive PCI Cuts Cardiac Risks from Vulnerable Plaques"

The PREVENT trial demonstrated that in patients with non–flow-limiting vulnerable plaques, percutaneous coronary intervention (PCI) plus optimal medical therapy reduced the risk for adverse cardiac events and death compared with optimal medical therapy alone. The study suggests a potential shift in the treatment paradigm for these types of lesions and supports consideration to expand indications for PCI to include non–flow-limiting, high-risk vulnerable plaques. Further research is needed to better identify which patients or lesions can benefit most from invasive or noninvasive imaging evaluation for detection of vulnerable plaques and the application of preventive PCI.

via Medscape|

#cardiac-events #clinical-trial #health