
Fit Bodies, Sharper Brains: Bigger BDNF Boosts With Exercise
A 12-week cycling program increases aerobic fitness and makes the brain release more BDNF in response to a single 15-minute workout; fitter participants show larger BDNF spikes and stronger prefrontal cortex activity during attention and inhibition tasks, with the boost tracking with VO2max gains, suggesting fitness amplifies the brain’s response to exercise.

