AI has been used to design toxic proteins, revealing biosecurity vulnerabilities that require ongoing vigilance to prevent potential threats, despite recent efforts to patch some weaknesses.
A HIV drug called maraviroc has shown promise in clearing out toxic proteins that lead to Huntington's disease and a type of dementia in mice. The drug has been found to restore the brain's ability to clear out protein clusters, reduce brain cell death, and slow down memory loss in mice genetically engineered to have dementia. The research identifies a biological pathway that leads to neurodegeneration and a potential way to stop it. However, it is still too early to say whether the drug can prevent dementia or Huntington's in humans.